Patent · US Expired

Diazepine derivatives

US4353827A · kind A · utility

67Cited by
1References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 18, 1982
Grant dateOct 12, 1982
Priority date
Expiry dateFeb 18, 2002

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D495/14
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

There is provided compounds which exhibit pronounced anticonvulsive and anxiolytic activities of the formula ##STR1## wherein A together with the two carbon atoms denoted as .alpha. and .beta. is the group ##STR2## B is dimethylene, trimethylene or propenylene, R.sup.1 is hydrogen, halogen, trifluoromethyl, amino, nitro, cyano or lower alkyl and R.sup.2 is hydrogen, halogen, trifluoromethyl, amino, nitro, cyano, lower alkyl, lower alkoxy, lower alkylthio, lower alkylsulphinyl or lower alkylsulphonyl, and the carbon atom denoted as .gamma. has the (S)--or (R,S)--configuration, and the pharmaceutically acceptable acid addition salts thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.