Patent · US Expired

5-[p-(Substituted)phenyl]-2,2-dialkyl-4-phenyl-3-oxazoline

US4360530A · kind A · utility

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Assignee

Inventors

Key dates

Filing dateNov 12, 1981
Grant dateNov 23, 1982
Priority date
Expiry dateNov 12, 2001

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D263/10
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of the formula ##STR1## wherein R.sup.1 and R.sup.2, independently, are hydrogen, halogen or lower alkyl; R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7, independently, are hydrogen or lower alkyl; R.sup.8 is hydrogen, lower alkyl or formyl; R.sup.9 and R.sup.10, independently, are methyl or trifluoromethyl; and n is 0 (zero) or, when both R.sup.7 and R.sup.8 are lower alkyl, n is 0 (zero) or 1, prepared, inter alia, from p-aminobenzaldehydes which may be N-alkyl substituted, are described. The compounds of formula I are orally active antidiabetic agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.