Phenyl-quinolizidines
US4391978A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 9, 1981 |
| Grant date | Jul 5, 1983 |
| Priority date | — |
| Expiry date | Apr 9, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D455/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Phenyl-quinolizidines of the general formula ##STR1## wherein X is hydrogen, fluorine, chlorine, lower-alkoxy, lower-alkyl or trifluoromethyl; Y is hydrogen, fluorine, chlorine, lower-alkoxy or lower-alkyl; and R.sup.1 is acyl, acylamino or a group A of the formula ##STR2## wherein R.sup.2 is oxygen or sulfur; R.sup.3 is hydrogen or lower-alkyl; and one of R.sup.4 and R.sup.5 is hydrogen and the other is bromine, iodine, cyano, lower-alkoxycarbonyl or sulfamoyl, as racemates or enatiomers, as well as acid addition salts thereof, utilizing various intermediates, are described. The foregoing compounds are useful as neuroleptic, antiemetic and analgesic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.