Nucleotidic sequence coding the surface antigen of the hepatitis B virus, vector containing said nucleotidic sequence, process allowing the obtention thereof and antigen obtained thereby
US4428941A · kind A · utility
62Cited by
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10Claims
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Key dates
| Filing date | Apr 30, 1981 |
| Grant date | Jan 31, 1984 |
| Priority date | — |
| Expiry date | Apr 30, 2001 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/223
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Nucleic acid of reduced size and vector containing said nucleotidic sequence of which DNA codes an immunogenic peptidic sequence capable of inducing the generation of antibodies to the virus of viral hepatitis B. It comprises totally or partly the sequence of nucleotides represented in FIG. 3A. Application to the production by cloning in a bacterium of an immunogenic protein immunizing against hepatitis B, or application to the obtention of probes for the diagnosis of the presence of Dane particles in a serum.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.