Beta-lactam compounds containing a protected C-acetyl group, process for their preparation and pharmaceutical compositions containing them
US4434099A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 11, 1981 |
| Grant date | Feb 28, 1984 |
| Priority date | — |
| Expiry date | Sep 11, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D411/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to new heterocyclic compounds containing a protected C-acetyl group. More particulary, the invention concerns new compounds of the formula (VI) ##STR1## wherein R.sup.1 is hydrogen or a group suitable for a temporary protection or amides, PA0 X is hydroxyl, halogen, cyano or an --O--SO.sub.2 --R.sup.2 group, in which PA0 R.sup.2 is lower alkyl or aryl, PA0 Y.sup.1 and Y.sup.2 together form a group suitable for a temporary protection of a keto group. The new compounds possess anaphylactic properties and are valuable intermediates of thienamycin synthesis. Their preparation and the new intermediates obtained during their preparation are also within the scope of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.