Inactivation of a lipid virus

US4511556A · kind A · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Robert H. Purcell · Boyds, US
• Stephen M. Feinstone · Boyds, US

Key dates

• Filing date: Jun 10, 1982
• Grant date: Apr 16, 1985
• Expiry date: Jun 10, 2002

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2770/24263
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method of inactivating a lipid virus in a protein carrier selected from the group consisting of Hepatitis B virus (HBV) and non-A, non-B hepatitis (NANBH) by contacting said virus for an extended period of time and ambient temperature with a halohydrocarbon treating agent preferably chloroform in an amount of 5% v/v to 50% v/v.