Isolation of hepatitis A virus strain HM-175

US4532215A · kind A · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Richard J. Daemer · Washington, US
• Stephen M. Feinstone · Boyds, US
• Ian D. Gust · Parramatta, AU
• Robert H. Purcell · Boyds, US

Key dates

• Filing date: Apr 7, 1982
• Grant date: Jul 30, 1985
• Expiry date: Apr 7, 2002

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Human hepatitis A virus (HAV), taken directly from human clinical specimens, can be isolated and serially passaged in primary African green monkey kidney (AGMK) cell cultures. This strain induced antibody to HAV in inoculated chimpanzees and is useful for vaccine.