Patent · US Expired

Saponin-based polyether polyols, pharmaceutical compositions and a method of using same

US4546097A · kind A · utility

6Cited by

12References

21Claims

0Family size

Assignee

The United States of America, as represented by the Department of Health and Human Services · US

Inventor

Josef Pitha · Baltimore, US

Key dates

Filing date	Nov 4, 1983
Grant date	Oct 8, 1985
Priority date	—
Expiry date	Nov 4, 2003

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07J71/0005
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Digitonin and digitonin-related saponins are derivatized by alkoxylation. The adducts have lower toxicity, higher solubility, and reduced ability to form insoluble complexes with cholesterol, as compared to the starting material. The adducts are particularly useful as solubilizing agents for lipophilic drugs and as mycoplasma suppressors in cell cultures.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.