Derivatives of 4-acetyl-3-hydroxy-2-alkyl-phenoxycarboxylic acids
US4672066A · kind A · utility
24Cited by
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43Claims
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Assignee
Inventors
Key dates
| Filing date | Apr 22, 1985 |
| Grant date | Jun 9, 1987 |
| Priority date | — |
| Expiry date | Apr 22, 2005 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D249/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to compounds of the formula ##STR1## wherein R is hydrogen or lower alkyl, Y is alkylene; Z is alkylene, ##STR2## the asterisk herein denotes bonding to the substituted acetophenone; R.sub.2 is hydrogen or lower alkoxy; and n is an integer of 1 to 3; A is ##STR3## and HET is a 5-or 6- membered nitrogen containing heterocyclic group, and their acid addition salts. The compounds of formula I of the invention are useful for the treatment of allergic conditions, such as, asthma and cardiovascular diseases, such as, angina and arrhythmias.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.