Radioimmuno detection of human cancers using anti-tumor monoclonal antibody
US4708862A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jun 17, 1986 |
| Grant date | Nov 24, 1987 |
| Priority date | — |
| Expiry date | Jun 17, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/809
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the radioimmuno detection of cancers by detecting tumor associated antigens and comprising the following steps: PA0 (i) preparing samples of hybridoma XMMCO-791 as herein described, PA0 (ii) separating and purifying the associated antibody produced by XMMCO-791 hybridomas to obtain the IgG2b isotype, PA0 (iii) labelling the antibody thus obtained with a radio active label, PA0 (iv) preparing composition containing an effective concentration of said labelled antibody PA0 (v) administering said antibody composition to a patient and PA0 (vi) thereafter screening said patient to detect concentrations of radioactivity thereby indicating a concentration of antibody. Hybridoma cell line XMMCO-791 was deposited with the American Type Culture Collection (A.T.C.C.), Rockville, MD 20852-1776, on Aug. 14, 1986, and given A.T.C.C. Accession No. HB 9173.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.