Patent assignee · US · COMPANY

Xoma Ltd.

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144Patents
0Active
144Granted
40Portfolio score

Filing activity: Oct 18, 1982 → Jul 16, 2002

Most-cited patents

PatentTitleAreaCited byStatus
US5500362A Chimeric antibody with specificity to human B cell surface antigen Chemistry; Metallurgy 777 Expired
US5766886A Modified antibody variable domains Physics 431 Expired
US5618920A Modular assembly of antibody genes, antibodies prepared thereby and use Chemistry; Metallurgy 290 Expired
US6204023A Modular assembly of antibody genes, antibodies prepared thereby and use Chemistry; Metallurgy 238 Expired
US5576184A Production of chimeric mouse-human antibodies with specificity to human tumor antigens Emerging Cross-Sectional Technologies 192 Expired
US5869619A Modified antibody variable domains Chemistry; Metallurgy 182 Expired
US5677180A Chimeric antibody with specificity to human B cell surface antigen Chemistry; Metallurgy 131 Expired
US5693493A Modular assembly of antibody genes, antibodies prepared thereby and use Chemistry; Metallurgy 128 Expired
US5698417A Modular assembly of antibody genes, antibodies prepared thereby and use Chemistry; Metallurgy 119 Expired
US5721108A Chimeric antibody with specificity to human B cell surface antigen Chemistry; Metallurgy 113 Expired
US4925922A Potentiation of cytotoxic conjugates Emerging Cross-Sectional Technologies 103 Expired
US4916213A Ribosomal inhibiting protein-immunoglobulin conjugates with specificity for tumor cell surface antigens, and mixtures thereof Emerging Cross-Sectional Technologies 86 Expired
US5348942A Therapeutic uses of bactericidal/permeability increasing protein products Human Necessities 81 Expired
US5698435A Modular assembly of antibody genes, antibodies prepared thereby and use Chemistry; Metallurgy 72 Expired
US5595898A Modular assembly of antibody genes, antibodies prepared thereby and use Chemistry; Metallurgy 71 Expired
US5846818A Pectate lyase signal sequence Chemistry; Metallurgy 70 Expired
US5576195A Vectors with pectate lyase signal sequence Chemistry; Metallurgy 69 Expired
US4489710A Composition and method for transplantation therapy Emerging Cross-Sectional Technologies 60 Expired
US4590071A Human melanoma specific immunotoxins Human Necessities 51 Expired
US5420019A Stable bactericidal/permeability-increasing protein muteins Chemistry; Metallurgy 47 Expired
US5028530A AraB promoters and method of producing polypeptides, including cecropins, by microbiological techniques Chemistry; Metallurgy 46 Expired
US5578572A Anti-gram-positive bacterial methods and materials Human Necessities 45 Expired
US5523288A Method of treating gram-negative bacterial infection by administration of bactericidal/permeability-increasing (BPI) protein product and antibiotic Emerging Cross-Sectional Technologies 44 Expired
US5821123A Modified antibody variable domains Physics 44 Expired
US5488034A Pharmaceutical composition comprising BPI proteins Human Necessities 39 Expired

Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.