Benzazecine derivatives for cognitive and memory functions
US4732979A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 21, 1987 |
| Grant date | Mar 22, 1988 |
| Priority date | — |
| Expiry date | Jan 21, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D225/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Benzazecinediones of the formula ##STR1## wherein R.sup.1 and R.sup.2 are independently hydrogen or chlorine, R.sup.3 is hydrogen, fluorine, chlorine, bromine or methoxy, R.sup.4 is hydrogen, chlorine or methoxy and R.sup.5 is hydrogen, acetyl, propionyl, benzoyl, chlorobenzoyl, methoxybenzoyl or phenylacetyl, with the proviso that 2 or 3 of the groups R.sup.1 to R.sup.4 are hydrogen. as well as many of the corresponding benzo[f]quinolines from which these benzazecinediones can be prepared by oxidation are suitable for the control or prevention of cerebral insufficiency or for the improvement of cognitive functions in mammals. They can be produced according to various processes and can be prepared into pharmaceutical compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.