Patent · US Expired

Benzo[f]quinoline intermediates

US4749791A · kind A · utility

8Cited by
3References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 18, 1987
Grant dateJun 7, 1988
Priority date
Expiry dateNov 18, 2007

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D225/06
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Benzazecinediones of the formula ##STR1## wherein R.sup.1 and R.sup.2 are independently hydrogen or chlorine, R.sup.3 is hydrogen, fluorine, chlorine, bromine or methoxy, R.sup.4 is hydrogen, chlorine or methoxy and R.sup.5 is hydrogen, acetyl, propionyl, benzoyl, chlorobenzoyl, methoxybenzoyl or phenylacetyl, with the proviso that 2 or 3 of the groups R.sup.1 to R.sup.4 are hydrogen, as well as many of the corresponding benzo[f]quinolines from which these benzazecinediones can be prepared by oxidation are suitable for the control or prevention of cerebral insufficiency or for the improvement of cognitive functions in mammals. They can be produced according to various processes and can be prepared into pharmaceutical compositions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.