Alkanoarachidonic acids
US4759880A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 27, 1984 |
| Grant date | Jul 26, 1988 |
| Priority date | — |
| Expiry date | Sep 27, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C62/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A series of alkanoarachidonic acids have been prepared as modulators of the arachidonic acid cascade to increase the production of biologically desirable compounds and minimize the production of biologically undesirable compounds. Examples of desirable compounds in this respect comprise postaglandins and thromboxanes whereas undesirable compounds comprise the mono- and polyhydroxyarachidonic acids and leukotrienes. The alkanoarachidonic acids and their intermediates are of the general formula: ##STR1## and at least one of X, Y, and Z is lower alkano and is hydrogen when not lower alkano; the esters and salts of the acids are also prepared. The acids, esters and salts may be used as anti-anaphylaxis or anti-thrombosis agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.