Pyrimidine derivatives for treating malaria
US4774249A · kind A · utility
19Cited by
4References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 23, 1987 |
| Grant date | Sep 27, 1988 |
| Priority date | — |
| Expiry date | Oct 23, 2007 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The pyrimidine derivatives of formula I ##STR1## wherein R.sup.1 is naphthyl, substituted naphthyl or substituted phenyl; R.sup.2 is hydrogen or lower alkoxy; and A is an optionally present ethylene or 1,3-propylene, and wherein the diaminopyridine group has the exo-configuration when A is present, are described. These compounds are useful as antibacterial agents, antimalarial agents and antitumor agents, and can be used in combination with sulfonamides in the control of bacterial infections.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.