Patent · US Expired

5-substituted-2',3'-dideoxycytidine compounds with anti-HTLV-III activity

US4788181A · kind A · utility

36Cited by
4References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 29, 1986
Grant dateNov 29, 1988
Priority date
Expiry dateSep 29, 2006

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D405/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

5-substituted 2',3'-dideoxycytidine compounds and their monophosphates are disclosed which have been found to have potent activity against retroviruses. The 5-fluoro-and 5-aza-substituted 2',3'-dideoycytidine compounds have been found to be effective against HTLV-III/LAV virus.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.