D-mannite derivatives as starting products for the synthesis of phospholipids
US4804789A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Oct 22, 1987 |
| Grant date | Feb 14, 1989 |
| Priority date | — |
| Expiry date | Oct 22, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/2458
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention concerns D-mannitol derivatives of the general formula I ##STR1## wherein R.sup.1 and R.sup.2 are the same or different, and when R.sup.1 R.sup.2 are the same, signify a straight-chained or branched alkyl, alkenyl or alkynyl group with 6 to 24 carbon atoms, which can contain cycloalkyl radicals with 3 to 6 carbon atoms, aryl radicals, benzyloxy, allyloxy, mesyloxy and/or halogen substituents and, when R.sup.1 and R.sup.2 are different, signify a straight-chained or branched alkyl group with 1 to 24 carbon atoms, which can contain cycloalkyl radicals with 3 to 6 carbon atoms, aryl radicals, benzyloxy, allyloxy, mesyloxy and/or halogen substituents, or a straight-chained or branched alkenyl or alkynyl group with 3 to 24 carbon atoms, which can contain cycloalkyl radicals with 3 to 6 carbon atoms, aryl radicals, benzyloxy, allyloxy, mesyloxy and/or halogen substituents, and R.sup.1 can also be trityl. Starting from these D-mannitol derivatives, there can be obtained, in simple manner and with good yields, phospholipids in the form of their optically pure stereoisomers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.