Administration of steroid hormones

US4877774A · kind A · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Josef Pitha · Baltimore, US
• Mitchell Harman · Ellicott City, US
• Kaneto Uekama · Kumamoto, JP

Key dates

• Filing date: Sep 9, 1987
• Grant date: Oct 31, 1989
• Expiry date: Sep 9, 2007

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B82Y5/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Crystalline complexes of steroid hormones with gamma-cyclodextrin are prepared by mixing the components together. Tablets can be formed from the complexes, which can be administered by contact with the mucosa to provide effective transfer of the hormones into the systemic circulation, gradually eliminating the hormones therefrom.