Phosphinic acid derivatives
US4885283A · kind A · utility
35Cited by
1References
38Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 1, 1987 |
| Grant date | Dec 5, 1989 |
| Priority date | — |
| Expiry date | Dec 1, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates compounds of the formula ##STR1## wherein R.sup.1 -R.sup.5 and X have the significance given in the description, and their pharmaceutically acceptable salts. The compounds of formula I inhibit the enzyme collagenase and can be used in the form of medicaments for the control or prevention of degenerative joint diseases such as rheumatoid arthritis and osteoarthritis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.