Phenyl glycines for use in reducing neurotoxic injury
US4918064A · kind A · utility
56Cited by
2References
42Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 21, 1987 |
| Grant date | Apr 17, 1990 |
| Priority date | — |
| Expiry date | Oct 21, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/4056
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A class of phenyl glycine compounds is described for treatment to reduce neurotoxic injury associated with anoxia or ischemia which typically follows stroke, cardiac arrest or perinatal asphyxia. The treatment includes administration of a phenyl glycine compound alone or in a composition in an amount effective as an antagonist to inhibit excitotoxic actions at major neuronal excitatory amino acid receptor sites.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.