Liquid chromatographic chiral stationary phase
US4919803A · kind A · utility
14Cited by
7References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 9, 1988 |
| Grant date | Apr 24, 1990 |
| Priority date | — |
| Expiry date | Dec 9, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C59/68
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A novel packing material for liquid chromatographic use is disclosed. This packing material is prepared by covalently bonding (S)- or (R)-6-methoxy-.alpha.-methyl-2-naphthaleneacetic acid (naproxen) to aminopropylsilanized silica. The resulting chiral stationary phase is effective for the resolution of enantiomeric (RS)-naproxen, and of other racemic .alpha.-methylarylacetic acids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.