Expression and purification of an HTLV-III gag/env gene protein
US4925784A · kind A · utility
21Cited by
4References
6Claims
0Family size
Assignee
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Key dates
| Filing date | Apr 4, 1986 |
| Grant date | May 15, 1990 |
| Priority date | — |
| Expiry date | Apr 4, 2006 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/826
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compositions are provided for the cloning and expression of plasmids bearing genes encoding a novel protein derived from HTLV-III. This protein, which is called the gag/env protein and which contains antigenic determinants from both the core and envelope proteins of HTLV-III, can be purified to homogeneity and used as the basis for diagnostic tests to detect the presence of antibodies against viruses associated with AIDS or the viruses themselves in human sera and other biological fluids. The gag/env protein may also be formulated for use as a vaccine for protection against AIDS through prophylactic immunization.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.