Dihydroxynaphthalene derivatives
US4937371A · kind A · utility
4Cited by
3References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 20, 1989 |
| Grant date | Jun 26, 1990 |
| Priority date | — |
| Expiry date | Oct 20, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C69/614
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There are described dihydroxy naphthalene derivatives of the formula ##STR1## in which R.sub.1 is hydrogen, lower alkyl or benzyl, R.sub.2 is hydrogen, hydroxy or lower alkanoyloxy, R.sub.3 is hydrogen or lower alkyl, R.sub.4 is hydrogen or halogen, R.sub.5 is hydrogen, acyl, methyl or benzyl, m is 0 or 1, and n is an integer from 2 to 10, as well as salts thereof with pharmaceutically acceptable bases when R.sub.1 is hydrogen. These compounds are useful as agents for the treatment of inflammatory bowel diseases, for instance, colitis, as pro-drugs, or as intermediates for the preparation of such compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.