Derivatives of hydroxyprimidines as leukotriene synthesis inhibitors
US4940712A · kind A · utility
14Cited by
3References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 26, 1989 |
| Grant date | Jul 10, 1990 |
| Priority date | — |
| Expiry date | May 26, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
2-Amino and 2-thio-4-substituted-5-(hydroxy or alkoxy)-pyrimidines, which may be 6-substituted, and derivatives thereof are disclosed. The compounds are inhibitors of leukotriene synthesis and are, therefore, useful for the treatment of pulmonary, inflammatory, dermatological, allergic and cardiovascular diseases. The compounds are also cytoprotective and therefore, useful in the treatment of peptic ulcers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.