Patent · US Expired

Expression of protein C

US4959318A · kind A · utility

49Cited by
4References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 29, 1986
Grant dateSep 25, 1990
Priority date
Expiry dateOct 29, 2006

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/849
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Genomic and cDNA sequences coding for a protein having substantially the same biological activity as human protein C and recombinant transfer vectors comprising these sequences are disclosed. Methods are disclosed for producing a protein which has substantially the same biological activity as human protein C. The protein, which may be in the form of activated protein C, is produced by mammalian host cells transfected with a plasmid capable of integration in mammalian host cell DNA. The plasmid includes a promoter followed downstream by a nucleotide sequence which encodes a protein having substantially the same structure and/or activity as human protein C, the nucleotide sequence being followed downstream by a polyadenylation signal.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.