Spontaneous vesticulation of multilamellar liposomes
US4963297A · kind A · utility
15Cited by
11References
10Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 22, 1987 |
| Grant date | Oct 16, 1990 |
| Priority date | — |
| Expiry date | Dec 22, 2007 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2984
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A new method is disclosed for making unilamellar vesicles from multilamellar vesicles. Such vesicles are formed without the use of physical of chemical disruption processes known in the art for forming unilamellar vesicles. The liposomes are incubated at neutral pH at or near the transition temperature of the lipids used, in low ionic strength media such as distilled water. The liposomes may comprise bioactive agents and may be used in vivo or in vitro.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.