Inventor · Vancouver, BC, CA

Thomas D. Madden

23Patents
17h-index
45Co-inventors
81Inventor score

Filing activity: Jul 26, 1985 → Oct 26, 2017

Most-cited inventions

PatentTitleAreaCited byStatus
US5885613A Bilayer stabilizing components and their use in forming programmable fusogenic liposomes Emerging Cross-Sectional Technologies 250 Expired
US5077056A Encapsulation of antineoplastic agents in liposomes Emerging Cross-Sectional Technologies 204 Expired
US4880635A Dehydrated liposomes Human Necessities 199 Expired
US5820873A Polyethylene glycol modified ceramide lipids and liposome uses thereof Emerging Cross-Sectional Technologies 150 Expired
US5736155A Encapsulation of antineoplastic agents in liposomes Human Necessities 101 Expired
US9139554B2 Amino lipids and methods for the delivery of nucleic acids Emerging Cross-Sectional Technologies 72 Active
US7811602B2 Liposomal formulations comprising dihydrosphingomyelin and methods of use thereof Human Necessities 64 Active
US6406713B1 Methods of preparing low-toxicity drug-lipid complexes Emerging Cross-Sectional Technologies 64 Expired
US5922350A Methods of dehydrating, storing and rehydrating liposomes Human Necessities 59 Expired
US6986902B1 Polyanionic polymers which enhance fusogenicity Chemistry; Metallurgy 58 Expired
US5616334A Low toxicity drug-lipid systems Emerging Cross-Sectional Technologies 58 Expired
US5578320A Method of dehydrating liposomes using protective sugars Human Necessities 46 Expired
US5837279A Encapsulation of ionizable agents in liposomes Human Necessities 38 Expired
US5858397A Liposomal formulations of mitoxantrone Human Necessities 33 Expired
US7060828B2 Liposomal camptothecins and uses thereof Human Necessities 28 Expired
US10653780B2 Amino lipids and methods for the delivery of nucleic acids Emerging Cross-Sectional Technologies 18 Active
US5389378A Benzoporphyrin vesicles and their use in photodynamic therapy Emerging Cross-Sectional Technologies 17 Expired
US4963297A Spontaneous vesticulation of multilamellar liposomes Emerging Cross-Sectional Technologies 15 Expired
US7244448B2 Liposomal antineoplastic drugs and uses thereof Human Necessities 13 Expired
US6673364B1 Liposome having an exchangeable component Emerging Cross-Sectional Technologies 9 Expired
US7311924B2 Compositions and methods for treating cancer Human Necessities 5 Expired
US7452550B2 Liposomal antineoplastic drugs and uses thereof Human Necessities 4 Expired
US11712481B2 Lipid nanoparticle formulations Chemistry; Metallurgy 2 Active

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.