Secretion of heterologous proteins
US4963495A · kind A · utility
36Cited by
4References
4Claims
0Family size
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Key dates
| Filing date | Oct 5, 1984 |
| Grant date | Oct 16, 1990 |
| Priority date | — |
| Expiry date | Oct 5, 2004 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/75
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Direct linkage of DNA encoding prokaryotic signals such as E. coli enterotoxin with DNA encoding mature eukaryotic proteins followed by transformation and culture of bacterial hosts characterized by a periplasmic space, yields substantial amounts of periplasmic mature protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.