Multilamellar liposomes having improved trapping efficiencies
US4975282A · kind A · utility
126Cited by
6References
28Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 17, 1987 |
| Grant date | Dec 4, 1990 |
| Priority date | — |
| Expiry date | Nov 17, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1277
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A multilamellar vesicle dispersed in an aqueous phase comprising an aqueous medium, a lipid concentration of at least about 50 mg/ml and a trapping efficiency of at least about 40 percent. The vesicle can be prepared by dispersing the lipid in an aqueous phase to form a multilamellar vesicle, rapidly freezing the multilamellar vesicle to obtain a frozen lipid-aqueous medium mixture, and warming the mixture to obtain a frozen and thawed multilamellar vesicle dispersed in an aqueous phase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.