Michael J. Hope
39Patents
28h-index
36Co-inventors
85Inventor score
Filing activity: Jul 26, 1985 → Oct 26, 2017
Most-cited inventions
| Patent | Title | Area | Cited by | Status |
|---|---|---|---|---|
| US5976567A | Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer | Human Necessities | 342 | Expired |
| US6815432B2 | Methods for encapsulating plasmids in lipid bilayers | Emerging Cross-Sectional Technologies | 303 | Expired |
| US5981501A | Methods for encapsulating plasmids in lipid bilayers | Emerging Cross-Sectional Technologies | 265 | Expired |
| US5008050A | Extrusion technique for producing unilamellar vesicles | Emerging Cross-Sectional Technologies | 239 | Expired |
| US6534484B1 | Methods for encapsulating plasmids in lipid bilayers | Emerging Cross-Sectional Technologies | 220 | Expired |
| US5204112A | Induction of asymmetry in vesicles | Emerging Cross-Sectional Technologies | 218 | Expired |
| US7422902B1 | Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer | Emerging Cross-Sectional Technologies | 212 | Expired |
| US5077056A | Encapsulation of antineoplastic agents in liposomes | Emerging Cross-Sectional Technologies | 204 | Expired |
| US4880635A | Dehydrated liposomes | Human Necessities | 199 | Expired |
| US6586410B1 | Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer | Emerging Cross-Sectional Technologies | 185 | Expired |
| US6858225B2 | Lipid-encapsulated polyanionic nucleic acid | Emerging Cross-Sectional Technologies | 185 | Expired |
| US6858224B2 | Method of preventing aggregation of a lipid:nucleic acid complex | Emerging Cross-Sectional Technologies | 145 | Expired |
| US4975282A | Multilamellar liposomes having improved trapping efficiencies | Human Necessities | 126 | Expired |
| US6287591A | Charged therapeutic agents encapsulated in lipid particles containing four lipid components | Emerging Cross-Sectional Technologies | 125 | Expired |
| US6835395B1 | Composition containing small multilamellar oligodeoxynucleotide-containing lipid vesicles | Emerging Cross-Sectional Technologies | 110 | Expired |
| US5736155A | Encapsulation of antineoplastic agents in liposomes | Human Necessities | 101 | Expired |
| US5753613A | Compositions for the introduction of polyanionic materials into cells | Chemistry; Metallurgy | 101 | Expired |
| US7341738B2 | Lipid-encapsulated polyanionic nucleic acid | Emerging Cross-Sectional Technologies | 87 | Expired |
| US5785987A | Method for loading lipid vesicles | Human Necessities | 83 | Expired |
| US9139554B2 | Amino lipids and methods for the delivery of nucleic acids | Emerging Cross-Sectional Technologies | 72 | Active |
| US7811602B2 | Liposomal formulations comprising dihydrosphingomyelin and methods of use thereof | Human Necessities | 64 | Active |
| US5965542A | Use of temperature to control the size of cationic liposome/plasmid DNA complexes | Human Necessities | 61 | Expired |
| US5922350A | Methods of dehydrating, storing and rehydrating liposomes | Human Necessities | 59 | Expired |
| US8021686B2 | Lipid-encapsulated polyanionic nucleic acid | Emerging Cross-Sectional Technologies | 58 | Active |
| US5785992A | Compositions for the introduction of polyanionic materials into cells | Human Necessities | 48 | Expired |
Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.