Antiviral and anticancer cyclopentenyl cytosine

US4975434A · kind A · utility

Assignee

• The United States of America as Represented by the Secretary of the Department of Health and Human Services · US

Inventors

• Victor E. Marquez · Gaithersburg, US
• John S. Driscoll · Rockville, US
• Mu-Ill Lim · Trumbull, US
• Christopher K. Tseng · Burtonsville, US
• Alberto Haces · Gaithersburg, US
• Robert I. Glazer · Gaithersburg, US

Key dates

• Filing date: Jan 31, 1989
• Grant date: Dec 4, 1990
• Expiry date: Jan 31, 2009

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Cyclopentenyl pyrimidine compounds have potent anti-viral, anti-tumor and differentiating activity. Of these compounds, cyclopentenyl cytosine has proved to be particularly effective in a variety of tumors, as well as having good antiviral activity and potent differentiating properties.