Flow-rate-controlled surface-charge coating for capillary electrophoresis
US5015350A · kind A · utility
45Cited by
4References
16Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 6, 1989 |
| Grant date | May 14, 1991 |
| Priority date | — |
| Expiry date | Nov 6, 2009 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/44752
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for achieving desired electroosmotic flow characteristics in a capillary tube having charged surface groups. An electrolyte solution containing a compound effective to stably alter the charge of the tube walls is drawn into and through the tube during while the electroosmotic flow rate in the tube is being monitored, until a desired electroosmotic flow rate is achieved. The method can be used to optimize electrophoretic separation of charged protein or nucleic acid species in a capillary tube, and to produce capillary tubes with desired charge density properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.