Patent assignee · US · COMPANY

Applied Biosystems, LLC

531Patents
420Active
531Granted
61Portfolio score

Filing activity: Mar 23, 1984 → Aug 26, 2020 · 227 expiring within 5 years

Most-cited patents

PatentTitleAreaCited byStatus
US4883750A Detection of specific sequences in nucleic acids Emerging Cross-Sectional Technologies 443 Expired
US5242794A Detection of specific sequences in nucleic acids Emerging Cross-Sectional Technologies 376 Expired
US5188934A 4,7-dichlorofluorescein dyes as molecular probes Emerging Cross-Sectional Technologies 297 Expired
US4757141A Amino-derivatized phosphite and phosphate linking agents, phosphoramidite precursors, and useful conjugates thereof Chemistry; Metallurgy 281 Expired
US5047524A Automated system for polynucleotide synthesis and purification Chemistry; Metallurgy 235 Expired
US8278071B2 Method for detecting the presence of a single target nucleic acid in a sample Emerging Cross-Sectional Technologies 223 Active
US5151510A Method of synethesizing sulfurized oligonucleotide analogs Chemistry; Metallurgy 219 Expired
US5366860A Spectrally resolvable rhodamine dyes for nucleic acid sequence determination Chemistry; Metallurgy 215 Expired
US4855225A Method of detecting electrophoretically separated oligonucleotides Chemistry; Metallurgy 211 Expired
US4811218A Real time scanning electrophoresis apparatus for DNA sequencing Physics 204 Expired
US8067159B2 Methods of detecting amplified product Emerging Cross-Sectional Technologies 202 Active
US5262530A Automated system for polynucleotide synthesis and purification Chemistry; Metallurgy 150 Expired
US7972778B2 Method for detecting the presence of a single target nucleic acid in a sample Emerging Cross-Sectional Technologies 130 Expired
US8431691B2 Reagents, methods, and libraries for bead-based sequencing Chemistry; Metallurgy 127 Active
US5470705A Probe composition containing a binding domain and polymer chain and methods of use Emerging Cross-Sectional Technologies 121 Expired
US7414118B1 Modified oligonucleotides and applications thereof Emerging Cross-Sectional Technologies 121 Active
US7635588B2 Apparatus and method for differentiating multiple fluorescence signals by excitation wavelength Emerging Cross-Sectional Technologies 121 Expired
US7480042B1 Luminescence reference standards Emerging Cross-Sectional Technologies 121 Expired
US8257925B2 Method for detecting the presence of a single target nucleic acid in a sample Emerging Cross-Sectional Technologies 101 Active
US4668476A Automated polypeptide synthesis apparatus Chemistry; Metallurgy 93 Expired
US8247221B2 Sample block apparatus and method for maintaining a microcard on sample block Emerging Cross-Sectional Technologies 91 Active
US7947477B2 Emulsion PCR and amplicon capture Performing Operations; Transporting 86 Active
US5514543A Method and probe composition for detecting multiple sequences in a single assay Emerging Cross-Sectional Technologies 83 Expired
US5374527A High resolution DNA sequencing method using low viscosity medium Emerging Cross-Sectional Technologies 82 Expired
US8058030B2 Methods of producing and sequencing modified polynucleotides Chemistry; Metallurgy 77 Active

Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.