Hybrid DNA synthesis of insulin
US5015575A · kind A · utility
21Cited by
3References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 13, 1990 |
| Grant date | May 14, 1991 |
| Priority date | — |
| Expiry date | Feb 13, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/036
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods and compositions are provided for efficient production of polypeptides having insulin activity. The proinsulin gene is joined to secretion and processing signals for expression and secretion in yeast. The product may be obtained in enhanced yield in the nutrient medium. Cell line pyinse was deposited at the A.T.C.C. on Apr. 6, 1983 and given Accession No. 20670.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.