Patent assignee · US · COMPANY

Chiron Corporation

681Patents
5Active
681Granted
46Portfolio score

Filing activity: Nov 18, 1982 → Feb 13, 2012 · 4 expiring within 5 years

Most-cited patents

PatentTitleAreaCited byStatus
US5124246A Nucleic acid multimers and amplified nucleic acid hybridization assays using same Emerging Cross-Sectional Technologies 646 Expired
US5367066A Oligonucleotides with selectably cleavable and/or abasic sites Chemistry; Metallurgy 516 Expired
US5597909A Polynucleotide reagents containing modified deoxyribose moieties, and associated methods of synthesis and use Chemistry; Metallurgy 429 Expired
US5860917A Method and apparatus for predicting therapeutic outcomes Emerging Cross-Sectional Technologies 385 Expired
US5635352A Solution phase nucleic acid sandwich assays having reduced background noise Emerging Cross-Sectional Technologies 361 Expired
US5118605A Polynucleotide determination with selectable cleavage sites Emerging Cross-Sectional Technologies 328 Expired
US5258506A Photolabile reagents for incorporation into oligonucleotide chains Chemistry; Metallurgy 318 Expired
US5094951A Production of glucose oxidase in recombinant systems Chemistry; Metallurgy 288 Expired
US4751180A Expression using fused genes providing for protein product Emerging Cross-Sectional Technologies 273 Expired
US5200314A Polynucleotide capture assay employing in vitro amplification Emerging Cross-Sectional Technologies 263 Expired
US5580731A N-4 modified pyrimidine deoxynucleotides and oligonucleotide probes synthesized therewith Emerging Cross-Sectional Technologies 259 Expired
US4510245A Adenovirus promoter system Chemistry; Metallurgy 242 Expired
US4868105A Solution phase nucleic acid sandwich assay Emerging Cross-Sectional Technologies 228 Expired
US5545730A Multifunctional nucleic acid monomer Chemistry; Metallurgy 225 Expired
US5656731A Nucleic acid-amplified immunoassay probes Emerging Cross-Sectional Technologies 221 Expired
US6054561A Antigen-binding sites of antibody molecules specific for cancer antigens Chemistry; Metallurgy 216 Expired
US5401465A Luminometer with reduced sample crosstalk Emerging Cross-Sectional Technologies 215 Expired
US6097831A Non-contract method for assay reagent volume dispense verification Emerging Cross-Sectional Technologies 215 Expired
US4775619A Polynucleotide determination with selectable cleavage sites Emerging Cross-Sectional Technologies 211 Expired
US5591584A N-4 modified pyrimidine deoxynucleotides and oligonucleotide probes synthesized therewith Emerging Cross-Sectional Technologies 208 Expired
US5552538A Oligonucleotides with cleavable sites Chemistry; Metallurgy 203 Expired
US5578717A Nucleotides for introducing selectably cleavable and/or abasic sites into oligonucleotides Chemistry; Metallurgy 187 Expired
US5460950A Expression of PACE in host cells and methods of use thereof Chemistry; Metallurgy 176 Expired
US5604130A Releasable multiwell plate cover Performing Operations; Transporting 169 Expired
US5681702A Reduction of nonspecific hybridization by using novel base-pairing schemes Chemistry; Metallurgy 169 Expired

Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.