Patent · US Expired

Antihyperlipidemic and antiatherosclerotic urea and carbamate compounds

US5015644A · kind A · utility

56Cited by
5References
31Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 1, 1989
Grant dateMay 14, 1991
Priority date
Expiry dateJun 1, 2009

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2601/08
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Certain substituted urea, thiourea, carbamate, and thiocarbamate compounds are potent inhibitors of the enzyme acyl-CoA: cholesterol acyltransferase and are thus useful agents for inhibiting the intestinal absorption of cholesterol, and for lowering blood plasma cholesterol.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.