Bruce D. Roth
76Patents
23h-index
111Co-inventors
91Inventor score
Filing activity: Dec 10, 1984 → Dec 2, 2022
Most-cited inventions
| Patent | Title | Area | Cited by | Status |
|---|---|---|---|---|
| US5273995A | [R-(R*R*)]-2-(4-fluorophenyl)-.beta.,.delta.-dihydroxy-5-( 1-methylethyl-3-phenyl-4-[(phenylamino) carbonyl]- 1H-pyrrole-1-heptanoic acid, its lactone form and salts thereof | Chemistry; Metallurgy | 392 | Expired |
| US5324483A | Apparatus for multiple simultaneous synthesis | Chemistry; Metallurgy | 266 | Expired |
| US4681893A | Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis | Human Necessities | 252 | Expired |
| US5385929A | [(Hydroxyphenylamino) carbonyl] pyrroles | Chemistry; Metallurgy | 152 | Expired |
| US4647576A | Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis | Chemistry; Metallurgy | 129 | Expired |
| US5003080A | Process for trans-6-(2-(substituted-pyrrol-1-yl)alkyl)pryan-2-one inhibitors of cholesterol synthesis | Chemistry; Metallurgy | 116 | Expired |
| US5097045A | Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis | Chemistry; Metallurgy | 85 | Expired |
| US5693657A | Heterocyclic-substituted alkyl amide acat inhibitors | Chemistry; Metallurgy | 83 | Expired |
| US5124482A | Process for trans-6-(2-substituted-pyrrol-1-yl)alkyl)pyran-2-one inhibitors of cholesterol synthesis | Chemistry; Metallurgy | 82 | Expired |
| US5149837A | Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis | Chemistry; Metallurgy | 75 | Expired |
| US5216174A | Process for trans-6-[12-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis | Chemistry; Metallurgy | 71 | Expired |
| US5280126A | Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis | Chemistry; Metallurgy | 63 | Expired |
| US5245047A | Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis | Chemistry; Metallurgy | 62 | Expired |
| US5015644A | Antihyperlipidemic and antiatherosclerotic urea and carbamate compounds | Chemistry; Metallurgy | 56 | Expired |
| US5981595A | Sulfonyl urea and carbamate ACAT inhibitors | Chemistry; Metallurgy | 41 | Expired |
| US6093744A | N-acyl sulfamic acid esters useful as hypocholesterolemic agents | Chemistry; Metallurgy | 40 | Expired |
| US6017905A | Phosphonamide ACAT inhibitors | Chemistry; Metallurgy | 39 | Expired |
| US6458781B1 | Substituted diarylalkyl amides as calcium channel antagonists | Chemistry; Metallurgy | 37 | Expired |
| US5612002A | Apparatus and method for multiple simultaneous synthesis | Chemistry; Metallurgy | 35 | Expired |
| US5958950A | Benzimidazole compounds useful for the treatment of inflammatory disease, atherosclerosis, restenosis or inhibiting lipoxygenase | Human Necessities | 32 | Expired |
| US4716175A | Saturated fatty acid amides as inhibitors of acyl-CoA:cholesterol acyltransferase | Chemistry; Metallurgy | 30 | Expired |
| US6117869A | Compounds for and methods of inhibiting matrix metalloproteinases | Chemistry; Metallurgy | 28 | Expired |
| US4906624A | 6-(((Substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis | Chemistry; Metallurgy | 27 | Expired |
| US6011052A | Pyrazolone derivatives as MCP-1 antagonists | Chemistry; Metallurgy | 20 | Expired |
| US4761419A | 6-(((substituted)quinolinyl)ethyl)-and ethenyl)tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis | Chemistry; Metallurgy | 20 | Expired |
Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.