AraB promoters and method of producing polypeptides, including cecropins, by microbiological techniques
US5028530A · kind A · utility
46Cited by
2References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 5, 1990 |
| Grant date | Jul 2, 1991 |
| Priority date | — |
| Expiry date | Feb 5, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A polynucleotide molecule expressible in a given host comprising the sequence of the araB promoter operably linked to a gene which is heterologous to said host. The heterologous gene codes for a peptide that is biologically active. The invention also relates to a genetic construct which comprises a first genetic sequence coding for cecropin operably linked to a second genetic sequence coding for a polypeptide which is capable of suppressing the bactericidal effect of the resulting fusion protein towards an otherwise cecropin sensitive bacterium.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.