Polypeptidic fractions inducing protective antibodies against malaria parasites and immunogenic compositions
US5032397A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 10, 1989 |
| Grant date | Jul 16, 1991 |
| Priority date | — |
| Expiry date | Jul 10, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/822
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An immunogenic composition for a vaccine against human malaria. The composition contains one or more polypeptides that can be extracted from a schizont form of a human-malaria parasite such as a Plasmodium falciparum. The polypeptides have a molecular weight of 40,000 to 140,000, and they react with protective antibodies which come from a monkey resistant to the malaria parasite and which can, by in vivo transfer to a monkey sensitive to the parasite, protect the sensitive monkey against the parasite.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.