Patent · US Expired

Polypeptidic fractions inducing protective antibodies against malaria parasites and immunogenic compositions

US5032397A · kind A · utility

5Cited by
3References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 10, 1989
Grant dateJul 16, 1991
Priority date
Expiry dateJul 10, 2009

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S530/822
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

An immunogenic composition for a vaccine against human malaria. The composition contains one or more polypeptides that can be extracted from a schizont form of a human-malaria parasite such as a Plasmodium falciparum. The polypeptides have a molecular weight of 40,000 to 140,000, and they react with protective antibodies which come from a monkey resistant to the malaria parasite and which can, by in vivo transfer to a monkey sensitive to the parasite, protect the sensitive monkey against the parasite.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.