Total synthesis of 20(S) and 20(R)-camptothecin and compthothecin derivatives
US5053512A · kind A · utility
68Cited by
9References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 17, 1990 |
| Grant date | Oct 1, 1991 |
| Priority date | — |
| Expiry date | Apr 17, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a method of producing 20(S)-comptothecin, 20(R)-camptothecin and analogs thereof. The method involves the resolution of an mixture of enantiomers of an intermediate lactone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.