Inventor · Chapel Hill, NC, US

Monroe E. Wall

25Patents
15h-index
13Co-inventors
74Inventor score

Filing activity: Mar 31, 1987 → Jun 30, 2003

Most-cited inventions

PatentTitleAreaCited byStatus
US4894456A Synthesis of camptothecin and analogs thereof Chemistry; Metallurgy 93 Expired
US5053512A Total synthesis of 20(S) and 20(R)-camptothecin and compthothecin derivatives Chemistry; Metallurgy 68 Expired
US4981968A Synthesis of camptothecin and analogs thereof Chemistry; Metallurgy 65 Expired
US5106742A Camptothecin analogs as potent inhibitors of topoisomerase I Chemistry; Metallurgy 65 Expired
US5180722A 10,11-methylenedioxy-20(RS)-camptothecin and 10,11-methylenedioxy-20(S)-camptothecin analogs Chemistry; Metallurgy 56 Expired
US5244903A Camptothecin analogs as potent inhibitors of topoisomerase I Chemistry; Metallurgy 56 Expired
US5049668A 10,11-methylenedioxy-20(RS)-camptothecin analogs Human Necessities 49 Expired
US5122526A Camptothecin and analogs thereof and pharmaceutical compositions and method using them Chemistry; Metallurgy 46 Expired
US5122606A 10,11-methylenedioxy camptothecins Chemistry; Metallurgy 35 Expired
US5646159A Water-soluble esters of camptothecin compounds Human Necessities 33 Expired
US5227380A Pharmaceutical compositions and methods employing camptothecins Chemistry; Metallurgy 28 Expired
US5364858A Camptothecin analogs as potent inhibitors of topoisomerase I Chemistry; Metallurgy 22 Expired
US5401747A Alkyl camptothecin compounds as potent inhibitors of human colorectal cancer Chemistry; Metallurgy 21 Expired
US5340817A Method of treating tumors with anti-tumor effective camptothecin compounds Chemistry; Metallurgy 20 Expired
US5496830A Inhibition of hemoflagellates by camptothecin compounds Emerging Cross-Sectional Technologies 17 Expired
US5916896A Water-soluble esters of camptothecin compounds Human Necessities 15 Expired
US6040313A Water-soluble esters of camptothecin compounds Human Necessities 14 Expired
US5614529A Inhibition of plasmodia parasites by camptothecin compounds Emerging Cross-Sectional Technologies 9 Expired
US5985888A Camptothecin compounds with combined topoisomarase I inhibition and DNA alkylation properties Chemistry; Metallurgy 8 Expired
US5932588A Camptothecin compounds with combined topoisomerase I inhibition and DNA alkylation properties Chemistry; Metallurgy 7 Expired
US6288072A Camptothecin .beta.-alanine esters with topoisomerase I inhibition Human Necessities 4 Expired
US6825206B1 Camptothecin compounds with a thioether group Human Necessities 2 Expired
US6268375A 10, 11-difluoromethylenedioxycamptothecin compounds with topoisomerase I inhibition Human Necessities 1 Expired
US7071204B2 Camptothecin analogs having an E-ring ketone Chemistry; Metallurgy 0 Expired
US7067666B2 7-substituted camptothecin and camptothecin analogs and methods for producing the same Human Necessities 0 Expired

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.