Glycerol derivatives
US5057530A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 19, 1989 |
| Grant date | Oct 15, 1991 |
| Priority date | — |
| Expiry date | May 19, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/088
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Glycerol derivatives of the formula ##STR1## wherein one of the residues R.sup.1, R.sup.2 and R.sup.3 is a group U of the formula OY.sup.1 or --X.sup.1 --CO--(A.sup.1).sub.n --Z.sup.1, another residue is a group V of the formula OY.sup.2 or --X.sup.2 --CO--(A.sup.2).sub.p --Z.sup.2, and the remaining residue is a group W of the formula --X.sup.3 T--(C.sub.2-6 -alkylene)-N.sup.+ R A.sup.- in which one of X.sup.1, X.sup.2 and X.sup.3 is oxygen or NQ.sup.1 and the other two are oxygen and the remaining symbols have the significance given below, and their hydrates are described and are prepared by introducing or generating the residues R.sup.1, R.sup.2 and R.sup.3 in corresponding glycerol derivatives. The compounds of formula I are active as inhibitors of blood platelet activating factor or as inhibitors of the growth of tumors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.