Protein crosslinking reagents cleavable within acidified intracellular vesicles
US5066490A · kind A · utility
24Cited by
10References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 1, 1988 |
| Grant date | Nov 19, 1991 |
| Priority date | — |
| Expiry date | Jun 1, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D493/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Crosslinking reagents for amino group-containing compounds are provided, which crosslinkers can be cleaved under mildly acidic conditions. The crosslinkers can be used to crosslink biologically active substances to be delivered to the cells, wherein the crosslinker will be cleaved in the mildly acidic conditions within the cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.