Activated polyers and conjugates thereof
US5081295A · kind A · utility
17Cited by
3References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 24, 1990 |
| Grant date | Jan 14, 1992 |
| Priority date | — |
| Expiry date | Aug 24, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G65/338
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Macromolecular species such as enzymes, proteins, drugs, and solid supports which contain reactive carbonyl groups or groups which are readily converted to reactive carbonyl groups are modified by reaction with a compound of the formula ##STR1## in which R.sup.1 is H, C.sub.1 -C.sub.20 alkyl, phenyl, (C.sub.1 -C.sub.10 alkyl)-substituted phenyl, or phenyl-substituted C.sub.1 -C.sub.10 alkyl; R.sup.2 is C.sub.2 -C.sub.5 alkylene or (C.sub.1 -C.sub.4 alkoxy)-substituted C.sub.2 -C.sub.5 alkylene; R.sup.3 is ##STR2## R.sup.4 is H or C.sub.1 -C.sub.4 alkyl; n is at least 5; and m is zero or 1.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.