Patent · US Expired

Novel methods and compositions for treatment of angiogenic diseases

US5086164A · kind A · utility

23Cited by
2References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 27, 1989
Grant dateFeb 4, 1992
Priority date
Expiry dateDec 27, 2009

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P9/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The subject invention pertains to the use of recombinant PF4 (rPF4) as well as full length novel analogs (mutants) of rPF4, and peptide fragments thereof, to inhibit angiogenesis. rPF4, analogs, and certain fragments are shown to have utility for treating angiogenic diseases and for the inhibition of endothelial cell proliferation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.