Repligen Corporation
130Patents
68Active
130Granted
55Portfolio score
Filing activity: May 24, 1982 → Mar 14, 2024 · 1 expiring within 5 years
Most-cited patents
| Patent | Title | Area | Cited by | Status |
|---|---|---|---|---|
| US5112946A | Modified PF4 compositions and methods of use | Human Necessities | 151 | Expired |
| US6444792B1 | CTLA4-C&ggr;4 fusion proteins | Chemistry; Metallurgy | 104 | Expired |
| US6020310A | Method for assisting in differential diagnosis and treatment of autistic syndromes | Physics | 81 | Expired |
| US6197746A | Method of using secretin for treating autism | Physics | 76 | Expired |
| US6498143B1 | Method for assisting in differential diagnosis and treatment of autistic syndromes | Physics | 63 | Expired |
| US6719972B1 | Methods of inhibiting T cell proliferation or IL-2 accumulation with CTLA4- specific antibodies | Chemistry; Metallurgy | 62 | Expired |
| US5151350A | Cloned genes encoding recombinant protein A | Human Necessities | 60 | Expired |
| US6790825B2 | Method of using secretin and compositions made therefrom for the treatment of autism and other neurological, behavioral and immunological disorders | Physics | 58 | Expired |
| US7091182B2 | Method for assisting in differential diagnosis and treatment of autistic syndromes | Physics | 58 | Expired |
| US6750334B1 | CTLA4-immunoglobulin fusion proteins having modified effector functions and uses therefor | Chemistry; Metallurgy | 46 | Expired |
| US5084559A | Protein A domain mutants | Emerging Cross-Sectional Technologies | 42 | Expired |
| US4935231A | Use of thioredoxin, thioredoxin-derived, or thioredoxin-like dithiol peptides in hair care preparations | Human Necessities | 36 | Expired |
| US6130316A | Fusion proteins of novel CTLA4/CD28 ligands and uses therefore | Chemistry; Metallurgy | 36 | Expired |
| US4776857A | Use of hydroxylated indoles as dye precursors | Human Necessities | 35 | Expired |
| US5260373A | Immobilized immunoglobulin-binding proteins | Human Necessities | 34 | Expired |
| US5858776A | Tumor cells with increased immunogenicity and uses therefor | Human Necessities | 33 | Expired |
| US4515773A | Skin tanning composition and method | Human Necessities | 28 | Expired |
| US5086164A | Novel methods and compositions for treatment of angiogenic diseases | Human Necessities | 23 | Expired |
| US5028419A | Use of thioredoxin, thioredoxin-derived, or thioredoxin-like dithiol peptides in hair care preparations | Human Necessities | 21 | Expired |
| US4855304A | Dinucleoside pyrophosphates and pyrophosphate homologs as plant antivirals | Human Necessities | 20 | Expired |
| US4687745A | Use of rLDM.TM. 1-6 and other ligninolytic enzymes in the treatment of mechanical pulps | Emerging Cross-Sectional Technologies | 19 | Expired |
| US4690895A | Use of rLDM.TM. 1-6 and other ligninolytic enzymes in the bleaching of kraft pulp | Textiles; Paper | 19 | Expired |
| US4746322A | Hair dye composition and process for using the same | Textiles; Paper | 19 | Expired |
| US5284827A | Systemic treatment of metastatic cancer with platelet factor 4 | Human Necessities | 16 | Expired |
| US4687741A | Novel enzymes which catalyze the degradation and modification of lignin | Emerging Cross-Sectional Technologies | 14 | Expired |
Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.