Vitamin D.sub.3 analogs
US5087619A · kind A · utility
39Cited by
3References
39Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 23, 1990 |
| Grant date | Feb 11, 1992 |
| Priority date | — |
| Expiry date | Mar 23, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/1804
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the formula ##STR1## wherein R is hydrogen or hydroxy, R.sub.5 is hydrogen, and A is --C.tbd.C--, ##STR2## or --CH.sub.2 --CH.sub.2 --, with the proviso that when A is --C.tbd.C--, R.sub.5 may also be deuterium, are described. The compounds of formula I are useful as agents for the treatment of hyperproliferative disorders of the skin such as psoriasis, as agents for the treatment of neoplastic diseases such as leukemia, and as agents for the treatment of sebaceous gland diseases such as acne or seborrheic dermatitis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.