Patent · US Expired

Renin inhibitors having all retro-inverted peptide bonds

US5095006A · kind A · utility

21Cited by

2References

9Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Wolfgang Bender · Wuppertal, DE
Gunther Kinast · Wuppertal, DE
Andreas Knorr · Erkrath, DE
Johannes-Peter Stasch · Wuppertal, DE

Key dates

Filing date	Jul 13, 1990
Grant date	Mar 10, 1992
Priority date	—
Expiry date	Jul 13, 2010

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C2601/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Renin-inhibiting peptides of the formula ##STR1## in which X represents a group of the formula ##STR2## represents hydroxyl, alkoxy having up to 8 carbon atoms, benzyloxy or a group of the formula --NR.sup.4 R.sup.5, PA0 A, B, D and E are identical or different and in each case PA1 represent a direct bond, PA1 represent a radical of the formula ##STR3## in which Q1 denotes oxygen, sulphur or the methylene group PA2 represent a grouping of the formula ##STR4## m represents a number 0, 1 or 2, and L represents a group of the formula --CH.sub.2 NR.sup.2 R.sup.3 and physiologically acceptable salts thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.