Patent · US Expired

Activated polymers and conjugates thereof

US5103039A · kind A · utility

13Cited by
0References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 19, 1991
Grant dateApr 7, 1992
Priority date
Expiry dateJun 19, 2011

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC08G65/338
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Macromolecular species such as enzymes, proteins, drugs, and solid supports which contain reactive carbonyl groups or groups which are readily converted to reactive carbonyl groups are modified by reaction with a compound of the formula ##STR1## in which R.sup.1 is H, C.sub.1 -C.sub.20 alkyl, phenyl, (C.sub.1 -C.sub.10 alkyl)-substituted phenyl, or phenyl-substituted C.sub.1 -C.sub.10 alkyl; R.sup.2 is C.sub.2 -C.sub.5 alkylene or (C.sub.1 -C.sub.4 alkoxy)-substituted C.sub.2 -C.sub.5 alkylene; R.sup.3 is ##STR2## R.sup.4 is H or C.sub.1 -C.sub.4 alkyl; n is at least 5; and m is zero or 1.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.