Activated polymers and conjugates thereof
US5103039A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 19, 1991 |
| Grant date | Apr 7, 1992 |
| Priority date | — |
| Expiry date | Jun 19, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G65/338
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Macromolecular species such as enzymes, proteins, drugs, and solid supports which contain reactive carbonyl groups or groups which are readily converted to reactive carbonyl groups are modified by reaction with a compound of the formula ##STR1## in which R.sup.1 is H, C.sub.1 -C.sub.20 alkyl, phenyl, (C.sub.1 -C.sub.10 alkyl)-substituted phenyl, or phenyl-substituted C.sub.1 -C.sub.10 alkyl; R.sup.2 is C.sub.2 -C.sub.5 alkylene or (C.sub.1 -C.sub.4 alkoxy)-substituted C.sub.2 -C.sub.5 alkylene; R.sup.3 is ##STR2## R.sup.4 is H or C.sub.1 -C.sub.4 alkyl; n is at least 5; and m is zero or 1.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.