Labile anchors for solid phase polynucleotide synthesis
US5112962A · kind A · utility
57Cited by
0References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 9, 1990 |
| Grant date | May 12, 1992 |
| Priority date | — |
| Expiry date | Nov 9, 2010 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention discloses a linker arm for solid support synthesis of oligonucleotides and oligonucleotide derivatives that allows the oligomers to be released relatively quickly under mild conditions. The linker arm comprises the following: ##STR1## The linker arm releases the oligomer in about one minute to about thirty minutes in a manner that leaves the oligonucleotide fully protected.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.